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500ug
| 产品编号 | bs-11378P |
| 英文名称 | Syntaxin 13 Antibody Blocking Peptide |
| 中文名称 | 神经突触素13封闭多肽 |
| 英文别名 | Syntaxin13; Syntaxin 13; Syntaxin-13; Syx13; Syx 13; Syx-13; CG11278; CT31479; Dm Syx13; ff16; l(3)01470; STX12_RAT. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Protein Trafficking > Vesicle Transport > SNAPs & SNAREs |
| 亚基 | Associates with the BLOC-1 complex. Interacts with BLOC1S6 (By similarity). Interacts with NAPA and SNAP23. Identified in a complex containing STX6, STX12, VAMP4 and VTI1A. |
| 亚细胞定位 | Membrane. Golgi apparatus > trans-Golgi network membrane. |
| 组织特异性 | Ubiquitous. Highly expressed in brain. |
| 相似性 | Belongs to the syntaxin family. Contains 1 t-SNARE coiled-coil homology domain. |
| 功能 | SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain C-terminal hydrophobic domains that direct them to their respective intracellular compartments. Syntaxin 12, also known as STX12, STX13 or STX14, is a 276 amino acid single-pass membrane protein that contains one t-SNARE coiled-coil homology domain and belongs to the Syntaxin family. Syntaxin 12 regulates protein transport between late endosomes and the trans-Golgi network and interacts with ABC1 (ATP-binding cassette transporter A1), a protein that facilitates cellular release of choline-phospholipids and cholesterol to apoA-I (apolipoprotein A-I). Found in recycling endosomes, Syntaxin 12 colocalizes with transferrin receptor and is encoded by a gene located on human chromosome 1. |
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Syntaxin 13 Antibody Blocking Peptide(bs-11378P)-500ug
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