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- Bioss
- bs-11354P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11354P |
| 英文名称 | Piccolo Antibody Blocking Peptide |
| 中文名称 | 神经细胞突触蛋白PCLO封闭多肽 |
| 英文别名 | ACZ; Aczonin; Brain-derived HLMN protein; DKFZp779G1236; KIAA0559; Multidomain presynaptic cytomatrix protein; PCLO; PCLO_HUMAN; Piccolo (presynaptic cytomatrix protein); Piccolo, mouse, homolog of antibody Pico; Presynaptic cytomatrix protein; Protein piccolo. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with RABAC1/PRA1, RIMS2 and profilin (By similarity). |
| 亚细胞定位 | Cell junction, synapse. Note=Concentrated at the presynaptic side of synaptic junctions. |
| 相似性 | Contains 2 C2 domains. Contains 1 PDZ (DHR) domain. |
| 功能 | May act as a scaffolding protein involved in the organization of synaptic active zones and in synaptic vesicle trafficking. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Piccolo is 1 component of the presynaptic cytomatrix. Bassoon is a large protein which is also found in the presynaptic compartments of rat brain synapses. Bassoon, along with Piccolo, is part of the ensemble of presynaptic proteins that are involved in orchestrating events at the nerve terminal. Bassoon is found in axon terminals of hippocampal neurons where it is highly concentrated in the vicinity of the active zone. Piccolo has a similar distribution and colocalizes with Bassoon in cultured hippocampal cells. Piccolo zinc fingers interact with the dual prenylated rab3A and VAMP2/ Synaptobrevin II receptor PRA. Bassoon may be involved in cytomatrix organization at the site of neurotransmitter release. The gene which encodes bassoon maps to human chromosome 3p21.31. The gene which encodes piccolo maps to human chromosome 7q21.11. |
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Piccolo Antibody Blocking Peptide(bs-11354P)-500ug
￥880
