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- Bioss
- bs-24129P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-24129P |
| 英文名称 | PTH2R Antibody Blocking Peptide |
| 中文名称 | 甲状旁腺激素相关受体蛋白2封闭多肽 |
| 英文别名 | Parathyroid hormone 2 receptor; Parathyroid hormone receptor precursor; PTH 2 receptor; PTH2 receptor; Pth2r; PTH2R_MOUSE; Pthr 2; Pthr2. |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Pathways and Processes > Cofactors, Vitamins / minerals > Vitamins / minerals Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR Signal Transduction > Growth Factors/Hormones > Hormones Signal Transduction > Metabolism > Vitamins / Minerals |
| 亚基 | Interacts (via N-terminal extracellular domain) with PTHLH and PTH. Homodimer in the absence of bound ligand. Peptide hormone binding leads to dissociation of the homodimer. Interacts (via C-terminus) with the heterodimer formed by GNG2 and GNB1. |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | Expressed abundantly in brain and pancreas. Also expressed in the testis. |
| 相似性 | Belongs to the G-protein coupled receptor 2 family. |
| 功能 | This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] |
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PTH2R Antibody Blocking Peptide(bs-24129P)-500ug
￥880
