- ￥880
- Bioss
- bs-11325P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11325P |
| 英文名称 | NOVA2 Antibody Blocking Peptide |
| 中文名称 | 神经肿瘤Nova2抗原封闭多肽 |
| 英文别名 | ANOVA; Astrocytic NOVA1 like RNA binding protein; Gm1424; NOVA2_HUMAN. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with PTBP2; the interaction is direct (By similarity). |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Brain. Expression restricted to astrocytes. |
| 相似性 | Contains 3 KH domains. |
| 功能 | NOVA2 may regulate RNA splicing or metabolism in a specific subset of developing neurons. It binds single strand RNA. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Nova-1 and Nova-2 are members of a superfamily of protein regulators of RNA metabolism in neurons. Both are nuclear RNA binding proteins with K homology motifs, conserved protein sequences which bind to RNA (1,2). Nova proteins, normally sequestered in the central nervous system, are expressed by systemic tumors in patients with the autoimmune disorder paraneoplastic opsoclonus-myoclonus ataxia (POMA) (3,4). Nova-1 is expressed in the hindbrain and ventral spinal cord and Nova-2 is expressed in the neocortex and hippocampus (4). Nova-1 is necessary for regulating neuron-specific alternative splicing of the glycine receptor Alpha2 pre-mRNA (5). |
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NOVA2 Antibody Blocking Peptide(bs-11325P)-500ug
￥880
