CX3CL1 Antibody Blocking Peptide(bs-0811P)-500ug

CX3CL1 Antibody Blocking Pepti

de(bs-0811P)-500ug
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  • ¥880
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  • bs-0811P
  • 2025年10月16日
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      500ug

    产品编号bs-0811P
    英文名称CX3CL1 Antibody Blocking Peptide
    中文名称CX3CL1封闭多肽
    英文别名C3Xkine; Chemokine C X3 C motif ligand 1; Chemokine CX3C Motif Ligand 1; CX3C membrane anchored chemokine; CXC 3; CXC3; CXC3C; FKN; Fractalkine; Neurotactin; NTN; NTT; SCYD 1; SCYD1; Small inducible cytokine D1; Small inducible cytokine subfamily D (Cys X3 Cys) member 1; Small inducible cytokine subfamily D member 1; X3CL1_HUMAN.
    性状Lyophilized
    纯化方法HPLC
    研究领域

    Cardiovascular > Atherosclerosis > Vascular Inflammation > Leukocyte recruitment > Chemokines

    Immunology > Innate Immunity > Chemokines > Delta Chemokines (CXC3)

    Immunology > Innate Immunity > Macrophage / Inflamm.

    亚基Monomer.
    亚细胞定位Cell membrane; Single-pass type I membrane protein. Processed fractalkine: Secreted.
    组织特异性Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.
    翻译后修饰A soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form.
    O-glycosylated with core 1 or possibly core 8 glycans.
    相似性Belongs to the intercrine delta family.
    功能The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料CX3CL1 is a member of the delta chemokine subfamily that contains a unique CX3C cysteine motif near the N-terminal. Unlike other known chemokines, it is a type 1 membrane protein containing a chemokine domain tethered on a long mucin-like stalk. CX3CL1, a leukocyte chemoattractant, is expressed in various tissues including the brain, heart, lung, kidney, skeletal muscle, and testis. The expression is reported to be up-regulated in endothelial cells and microglia by inflammatory signals. CX3CR1, a specific receptor for fractalkine, mediates both leukocyte migration and adhesion.

     

     

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