BSPRY Antibody Blocking Peptide(bs-12639P)-500ug

BSPRY Antibody Blocking Peptid

e(bs-12639P)-500ug
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  • bs-12639P
  • 2025年10月16日
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      500ug

    产品编号bs-12639P
    英文名称BSPRY Antibody Blocking Peptide
    中文名称BSPRY蛋白封闭多肽
    英文别名B box and SPRY domain containing; B box and SPRY domain containing protein; B box and SPRY domain-containing protein; B-box and SPRY domain containing; Bspry; BSPRY_HUMAN; FLJ20150; Zetin 1.
    纯化方法HPLC
    研究领域

    Metabolism > Types of disease > Cancer

    Signal Transduction > Adapters > Cytoplasmic

    Signal Transduction > Metabolism > Plasma Membrane > Channels

    亚细胞定位Cytoplasm. Membrane.
    相似性Contains 1 B box-type zinc finger.
    Contains 1 B30.2/SPRY domain.
    功能BSPRY is a 402 amino acid protein that localizes to both the membrane and the cytoplasm and contains one B box-type zinc finger and one B30.2/SPRY domain. Existing as two alternatively spliced isoforms, BSPRY interacts with TRPV5 and TRPV6 and is thought to regulate the transport of calcium across the epithelium, probably by inhibiting the activity of TRPV proteins. The gene encoding BSPRY maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料BSPRY is a 402 amino acid protein that localizes to both the membrane and the cytoplasm and contains one B box-type zinc finger and one B30.2/SPRY domain. Existing as two alternatively spliced isoforms, BSPRY interacts with TRPV5 and TRPV6 and is thought to regulate the transport of calcium across the epithelium, probably by inhibiting the activity of TRPV proteins. The gene encoding BSPRY maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.

     

     

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