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- Bioss
- bs-24109P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-24109P |
| 英文名称 | GSTM1 Antibody Blocking Peptide |
| 中文名称 | 谷胱甘肽转移酶封闭多肽 |
| 英文别名 | Glutathione S-Transferase Mu 1; Glutathione S-Transferase M1; GST HB Subunit 4; GST Class-Mu 1; EC 2.5.1.18; GSTM1a-1a; GSTM1b-1b; GSTM1-1; GST1; GTH4; S-(Hydroxyalkyl)Glutathione Lyase; Glutathione S-Aralkyltransferase; Glutathione S-Alkyltransferase; Glutathione S-Aryltransferase; HB Subunit 4; GTM1; MU-1; H-B; MU; GSTM1_MOUSE; |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Pathways and Processes > Metabolic signaling pathways > Drug metabolism Signal Transduction > Metabolism > Drug metabolism Tags & Cell Markers > Cell Type Markers > Tumor Associated |
| 亚基 | Homodimer. |
| 亚细胞定位 | Cytoplasm |
| 组织特异性 | Liver (at protein level). |
| 相似性 | Belongs to the GST superfamily. Mu family. |
| 功能 | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008] |
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GSTM1 Antibody Blocking Peptide(bs-24109P)-500ug
￥880
