SAA1 Antibody Blocking Peptide(bs-24107P)-500ug

SAA1 Antibody Blocking Peptide

(bs-24107P)-500ug
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  • bs-24107P
  • 2025年10月16日
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      500ug

    产品编号bs-24107P
    英文名称SAA1 Antibody Blocking Peptide
    中文名称血清淀粉样蛋白A封闭多肽
    英文别名amyloid A, serum; Amyloid fibril protein AA; Amyloid protein A; MGC111216; PIG4; SAA; SAA2; Serum amyloid A protein; serum amyloid A-1 protein; serum amyloid A1; TP53I4; Tumor protein p53 inducible protein 4.
    纯化方法HPLC
    研究领域

    Cardiovascular > Lipids / Lipoproteins > Lipoproteins/Apolipoproteins > Apolipoproteins

    Immunology > Innate Immunity > Complement > Regulatory

    Immunology > Innate Immunity > Cytokines

    Immunology > Innate Immunity > Macrophage / Inflamm.

    Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR

    亚基Homohexamer; dimer of trimers. Can form amyloid fibrils after partial proteolysis; the native, undenatured protein does not form amyloid fibrils (in vitro). Apolipoprotein of the HDL complex. Binds to heparin.
    亚细胞定位Secreted.
    组织特异性Expressed by the liver; secreted in plasma (at protein level).
    翻译后修饰This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end.
    功能Major acute phase reactant. Apolipoprotein of the HDL complex.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Jun 2012]

     

     

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