- ￥880
- Bioss
- bs-16715P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-16715P |
| 英文名称 | TENT4B Antibody Blocking Peptide |
| 中文名称 | 拓扑异构酶相关功能蛋白4-2封闭多肽 |
| 英文别名 | PAP-associated domain-containing protein 5; Terminal uridylyltransferase 3; Topoisomerase related function protein 4-2; TRF4-2; PAPD5_HUMAN; TUTase 3. |
| 纯化方法 | HPLC |
| 亚基 | Component of a nucleolar TRAMP-like complex, an ATP-dependent exosome regulatory complex consisting of an helicase |
| 亚细胞定位 | Nuclear |
| 相似性 | Belongs to the DNA polymerase type-B-like family. Contains 1 PAP-associated domain. |
| 功能 | Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity (in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Plays a role in replication-dependent histone mRNA degradation. May be involved in the terminal uridylation of mature histone mRNAs before their degradation is initiated. DNA polymerase, probably involved in DNA repair. May play a role in sister chromatid cohesion |
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TENT4B Antibody Blocking Peptide(bs-16715P)-500ug
￥880
