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- 规格:
500ug/1mg
| 规格: | 500ug | 产品价格: | ¥880.0 |
|---|---|---|---|
| 规格: | 1mg | 产品价格: | ¥1380.0 |
| 产品编号 | bs-0071P |
| 英文名称 | NPY Antibody Blocking Peptide |
| 中文名称 | 神经肽Y封闭多肽 |
| 英文别名 | Neuropeptide tyrosine; Neuropeptide Y precursor; NPY; PYY 4; PYY4; Y Neuropeptide; Pro-neuropeptide Y; NPY_HUMAN. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Angiogenesis > Angiogenic Factors Cardiovascular > Heart > Contractility > Inotropics Cardiovascular > Heart > Hypertrophy Cardiovascular > Vasculature > Vasoconstriction Neuroscience > Neurology process > Metabolism Neuroscience > Neurotransmitter > Neuropeptides > Hormones Neuroscience > Neurotransmitter > Neuropeptides > More Neuropeptides |
| 亚细胞定位 | Secreted. |
| 组织特异性 | One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla. |
| 翻译后修饰 | The neuropeptide Y form is cleaved at Pro-30 by the prolyl endopeptidase FAP (seprase) activity (in vitro). |
| 相似性 | Belongs to the NPY family. |
| 功能 | NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014] |
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NPY Antibody Blocking Peptide(bs-0071P)-500ug/1mg
¥880 - 1380







