CGNL1 Antibody Blocking Peptide(bs-13881P)-500ug

CGNL1 Antibody Blocking Peptid

e(bs-13881P)-500ug
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  • bs-13881P
  • 2025年10月16日
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      500ug

    产品编号bs-13881P
    英文名称CGNL1 Antibody Blocking Peptide
    中文名称结蛋白样蛋白CGNL1封闭多肽
    英文别名Cgnl1; CGNL1_HUMAN; Cingulin like 1; Cingulin-like protein 1; FLJ14957; JACOP; Junction-associated coiled-coil protein; KIAA1749; MGC138254; Paracingulin.
    纯化方法HPLC
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Tight Junctions

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microfilaments > Actin etc > Actin

    亚细胞定位Cell junction > tight junction. Localizes to the apical junction complex composed of tight and adherens junctions.
    组织特异性Smooth muscle, spleen, testis, fetal brain, amygdala, corpus callosum, cerebellum, thalamus and subthalamic nucleus of adult brain.
    相似性Belongs to the cingulin family.
    功能May be involved in anchoring the apical junctional complex, especially tight junctions, to actin-based cytoskeletons.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a member of the cingulin family. The encoded protein localizes to both adherens and tight cell-cell junctions and mediates junction assembly and maintenance by regulating the activity of the small GTPases RhoA and Rac1. Heterozygous chromosomal rearrangements resulting in association of the promoter for this gene with the aromatase gene are a cause of aromatase excess syndrome. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Nov 2011]

     

     

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