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500ug
| 产品编号 | bs-11303P |
| 英文名称 | HCRT Antibody Blocking Peptide |
| 中文名称 | 增食欲素B/欲激素B封闭多肽 |
| 英文别名 | HCRT; Hcrt2; Orexin 2; Orexin-2; hypocretin (orexin) neuropeptide precursor; Hypocretin 2; hypocretin; NRCLP1; Orexin; Orexin precursor; OX; PPOX; prepro orexin; OREX_HUMAN; PPORX. |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Types of disease > Obesity Neuroscience > Neurology process > Metabolism Neuroscience > Neurotransmitter > Neuropeptides > Hormones |
| 亚细胞定位 | Cytoplasmic and Endoplasmic reticulum |
| 组织特异性 | Abundantly expressed in subthalamic nucleus but undetectable in other brain regions tested (hypothalamus was not tested) and in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| 翻译后修饰 | Specific enzymatic cleavages at paired basic residues yield the different active peptides. |
| 相似性 | Belongs to the orexin family. |
| 功能 | Prepro-orexin is 130 amino acid long peptide with a putative 33 AA secretory sequence, a hydrophobic core followed by residues with small polar side chains. The expression was detected in brain and to a small extent in testis. These neuropeptides bind and activate two closely related Orexin receptors—G-protein coupled receptors (GPCRs) OX1R and OX2R. Orexins (Orexin A and Orexin B) are a family of hypothalamic neuropeptides selectively expressed in the hypothalamus. Orexin A and Orexin B are derived from the same precursor (Prepro-orexin) by proteolytic cleavage. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Prepro-orexin is 130 amino acid long peptide with a putative 33 AA secretory sequence, a hydrophobic core followed by residues with small polar side chains. The expression was detected in brain and to a small extent in testis. These neuropeptides bind and activate two closely related Orexin receptors—G-protein coupled receptors (GPCRs) OX1R and OX2R. Orexins (Orexin A and Orexin B) are a family of hypothalamic neuropeptides selectively expressed in the hypothalamus. Orexin A and Orexin B are derived from the same precursor (Prepro-orexin) by proteolytic cleavage. |
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HCRT Antibody Blocking Peptide(bs-11303P)-500ug
¥880







