HCRT Antibody Blocking Peptide(bs-11303P)-500ug

HCRT Antibody Blocking Peptide

(bs-11303P)-500ug
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  • ¥880
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  • bs-11303P
  • 2025年10月16日
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      500ug

    产品编号bs-11303P
    英文名称HCRT Antibody Blocking Peptide
    中文名称增食欲素B/欲激素B封闭多肽
    英文别名HCRT; Hcrt2; Orexin 2; Orexin-2; hypocretin (orexin) neuropeptide precursor; Hypocretin 2; hypocretin; NRCLP1; Orexin; Orexin precursor; OX; PPOX; prepro orexin; OREX_HUMAN; PPORX.
    纯化方法HPLC
    研究领域

    Metabolism > Types of disease > Obesity

    Neuroscience > Neurology process > Metabolism

    Neuroscience > Neurotransmitter > Neuropeptides > Hormones

    亚细胞定位Cytoplasmic and Endoplasmic reticulum
    组织特异性Abundantly expressed in subthalamic nucleus but undetectable in other brain regions tested (hypothalamus was not tested) and in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas.
    翻译后修饰Specific enzymatic cleavages at paired basic residues yield the different active peptides.
    相似性Belongs to the orexin family.
    功能Prepro-orexin is 130 amino acid long peptide with a putative 33 AA secretory sequence, a hydrophobic core followed by residues with small polar side chains. The expression was detected in brain and to a small extent in testis. These neuropeptides bind and activate two closely related Orexin receptors—G-protein coupled receptors (GPCRs) OX1R and OX2R. Orexins (Orexin A and Orexin B) are a family of hypothalamic neuropeptides selectively expressed in the hypothalamus. Orexin A and Orexin B are derived from the same precursor (Prepro-orexin) by proteolytic cleavage.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Prepro-orexin is 130 amino acid long peptide with a putative 33 AA secretory sequence, a hydrophobic core followed by residues with small polar side chains. The expression was detected in brain and to a small extent in testis. These neuropeptides bind and activate two closely related Orexin receptors—G-protein coupled receptors (GPCRs) OX1R and OX2R. Orexins (Orexin A and Orexin B) are a family of hypothalamic neuropeptides selectively expressed in the hypothalamus. Orexin A and Orexin B are derived from the same precursor (Prepro-orexin) by proteolytic cleavage.

     

     

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