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- bs-1641P
- 2025年10月16日
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500ug
| 产品编号 | bs-1641P |
| 英文名称 | Phospho-GAP43 (Ser41) Antibody Blocking Peptide |
| 中文名称 | 磷酸化神经生长相关蛋白43封闭多肽 |
| 英文别名 | GAP43 (phospho S41); p-GAP43 (phospho S41); Phospho-GAP43（pSer41）; GAP43 (Phospho-Ser41); p-GAP43 (Ser41); p-GAP43 (S41); Growth Associated Protein-43; Neuromodulin; Axonal membrane protein GAP 43; B-50; F1; GAP 43; Growth Associated Protein 43; Nerve Growth Related Peptide; Neural phosphoprotein B 50; Neuromodulin; GAP-43; pp46; NEUM_HUMAN; Protein F1; QtrA-11580; QtrA-13071. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Cell Type Marker > Neuron marker > Growth Cone Neuroscience > Cell Type Marker > Neuron marker > Synapse marker Neuroscience > Neurology process > Growth and Development > Axonal Guidance Proteins |
| 亚基 | Identified in a complex containing FGFR4, NCAM1, CDH2, PLCG1, FRS2, SRC, SHC1, GAP43 and CTTN. Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence. |
| 亚细胞定位 | Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Cell projection, filopodium membrane; Peripheral membrane protein. Note=Cytoplasmic surface of growth cone and synaptic plasma membranes. |
| 翻译后修饰 | Phosphorylated at Ser-41 by PHK. Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity.
Palmitoylation by ARF6 is essential for plasma membrane association and axonal and dendritic filopodia induction. Deacylated by LYPLA2. |
| 相似性 | Belongs to the neuromodulin family. Contains 1 IQ domain. |
| 功能 | This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Phospho-GAP43 (Ser41) Antibody Blocking Peptide(bs-1641P)-500ug
￥1080
