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1mg/2mg
| 规格: | 1mg | 产品价格: | ¥2600.0 |
|---|---|---|---|
| 规格: | 2mg | 产品价格: | ¥4000.0 |
| 产品编号 | bs-1698P |
| 英文名称 | Human ox-LDL |
| 中文名称 | 氧化低密度脂蛋白 |
| 英文别名 | ox-LDL: LDL (Copper oxidized); Cu2SO4 oxidized low density lipoprotein; oxidized low density lipoprotein; Low density lipoprotein; MDA oxidized LDL; MDA oxidized low density lipoprotein; Human ox-LDL |
| 中文别名 | 氧化型低密度脂蛋白; |
| 性状 | Liquid |
| 浓度 | >1.0 mg/ml |
| 储存液 | 10 mM PBS(pH=7.4) with 0.01 μM EDTA. |
| 亚细胞定位 | Secreted. |
| 保存条件 | Store at 4°C for 8-20 weeks. Avoid freeze. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. Low-density lipoprotein oxidised with Cu2SO4. |

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文献和实验[IF={{ 6.986 }}] {Yang, Yilin. et al. Knockdown of lncRNA H19 alleviates ox-LDL-induced HCAECs inflammation and injury by mediating miR-20a-5p/HDAC4 axis. INFLAMM RES. 2022 Jul;:1-13} {Other} {}
[IF={{ 3.647 }}] {Yi Zhou et al. Long non-coding RNA MIAT/miR-148b/PAPPA axis modifies cell proliferation and migration in ox-LDL-induced Human aorta vascular smooth muscle cells. Life Sci. 2020 Sep 1;256:117852.} {Other} {Human}
[IF={{ 3.514 }}] {Su Q et al. Pinocembrin protects endothelial cells from oxidized LDL-induced injury.Cytokine. 2018 Nov;111:475-480.} {Other} {}
[IF={{ 3.466 }}] {Zhang et al. H19 knockdown suppresses proliferation and induces apoptosis by regulating miR-148b/WNT/β-catenin in ox-LDL -stimulated vascular smooth muscle cells. (2018) J.Biomed.Sci. 25:11} {Other} {Human}
[IF={{ 3.4 }}] {Jiaju Sun. et al. IGFBP7 mediates oxLDL-induced human vascular endothelial cell injury by suppressing the expression of SIRT1. HELIYON. 2024 Aug;10:} {Other} {}
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