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- Bioss
- bs-12602P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-12602P |
| 英文名称 | phospho-PDLIM5 (Tyr251) Antibody Blocking Peptide |
| 中文名称 | 磷酸化PDZ和LIM结构域结合蛋白5封闭多肽 |
| 英文别名 | PDLIM5 (phospho Y251); p-PDLIM5 (phospho Y251); ENH; ENH1; Enigma homolog; Enigma like LIM domain protein; Enigma like PDZ and LIM domains protein; Enigma-like PDZ and LIM domains protein; L 9; L9; LIM; PDLI5_HUMAN; PDLIM5; PDZ and LIM domain 5; PDZ and LIM domain protein 5. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurotransmission > Secretory Vesicles Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microfilaments > Actin etc > Actin Binding Proteins Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > PKC Signal Transduction > Signaling Pathway > Calcium Signaling |
| 亚细胞定位 | Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse > synaptosome. Cytoplasm. Detected both at presynaptic and postsynaptic sites. |
| 组织特异性 | Heart and skeletal muscle specific. Expression is commonly increased in the brain of patients with bipolar disorder, schizophrenia, and major depression. |
| 相似性 | Contains 3 LIM zinc-binding domains. Contains 1 PDZ (DHR) domain. |
| 功能 | May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May restrain postsynaptic growth of excitatory synapses. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012] |
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phospho-PDLIM5 (Tyr251) Antibody Blocking Peptide(bs-12602P)-500ug
￥1080
