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| 产品编号 | bs-8074P |
| 英文名称 | ANKRD1 Antibody Blocking Peptide |
| 中文名称 | 心肌锚蛋白重复结构域1封闭多肽 |
| 英文别名 | ALRP; ANKR1_HUMAN; ANKRD 1; ANKRD1; Ankyrin repeat domain 1 (cardiac muscle); Ankyrin repeat domain containing protein 1; Ankyrin repeat domain-containing protein 1; C 193; C193; Cardiac ankyrin repeat protein; CARP; CVARP; Cytokine inducible nuclear protein; Cytokine-inducible gene C-193 protein; Cytokine-inducible nuclear protein; HA1A2; Liver ankyrin repeat domain 1; MCARP. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Heart > Cardiogenesis > Transcription factors/regulators Epigenetics and Nuclear Signaling > Transcription > Other factors |
| 亚基 | Interacts with YBX1 (By similarity). Interacts with TTN/titin. |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells. |
| 相似性 | Contains 5 ANK repeats. |
| 功能 | May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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