GPR1 Rabbit pAb, Biotin conjugated(bs-12019R-Bio)-100ul

GPR1 Rabbit pAb, Biotin conjug

ated(bs-12019R-Bio)-100ul
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  • ￥2980
  • Bioss已认证
  • bs-12019R-Bio
  • 2025年10月15日
  • 产品信息以Bioss网站为准
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北京博奥森生物技术有限公司
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    • 规格：

      100ul

    产品编号bs-12019R-Bio
    英文名称GPR1 Rabbit pAb, Biotin conjugated
    中文名称Biotin标记的G蛋白偶联受体1抗体
    英文别名G protein coupled receptor 1; G-protein coupled receptor 1; GPR1; GPCR1/GPR1; GPR1_HUMAN.
    产品应用ELISA=1:500-5000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human GPR1
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR

    亚细胞定位Cell membrane.
    组织特异性Expressed in hippocampus.
    相似性Belongs to the G-protein coupled receptor 1 family.
    功能Receptor for the inflammation-associated leukocyte chemoattractant chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation. Can act as a coreceptor for HIV-1.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    背景资料G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. Gpr1 is required for yeast-to-hypha transition on various solid hypha-inducing media, and important for yeast cell morphology. It activates guanine nucleotide exchange on Gpa2 which stimulates cAMP synthesis by glucose. In Saccharomyces cerevisiae, Gpr1 is necessary for filamentous and invasive growth.

     

    应用推荐稀释比例
    {ELISA}{1:500-5000}

     

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