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PLP1 Rabbit pAb, PE conjugated

(bs-11093R-PE)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-11093R-PE
  • 2025年10月15日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-11093R-PE
    英文名称PLP1 Rabbit pAb, PE conjugated
    中文名称PE标记的髓磷酯髓鞘蛋白1抗体
    英文别名MYPR_HUMAN; Myelin proteolipid protein; PLP; Lipophilin; proteolipid protein 1; PMD; HLD1; MMPL; SPG2; GPM6C; PLP/DM20;
    产品应用ICC/IF=1:50-200, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Myelin proteolipid protein
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Neuroscience > Cell Adhesion Proteins > Membrane Proteins

    Neuroscience > Cell Type Marker > Glia marker > Oligodendrocyte marker

    Tags & Cell Markers > Cell Type Markers > Neuroscience Markers > Glial

    亚基Belongs to the myelin proteolipid protein family.
    亚细胞定位Membrane; Multi-pass membrane protein.
    相似性Belongs to the myelin proteolipid protein family.
    功能This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    背景资料PLP is a major constituent of myelin. The two isoforms of the myelin proteolipid protein, PLP and DM20, are very hydrophobic integral membrane proteins that account for about half of the protein content of adult CNS myelin. A mutation in the gene which encodes PLP is linked to Pelizaeus-Merzbacher disease (PMD), a chronic infantile type of diffuse cerebral sclerosis. The gene which encodes PLP maps to human chromosome Xq22. The glycoprotein zero (also designated P-zero or myelin peripheral protein) is the primary structural protein of peripheral myelin, and accounts for more than 50% of the protein present in the peripheral nerve sheath. Zero is an integral membrane glycoprotein. Expression of zero is restricted to Schwann cells. The gene which encodes zero maps to human chromosome 1q22. PMP22 (peripheral myelin protein 22) is a growth-regulated membrane protein which is expressed by Schwann cells and is localized primarily in compact peripheral nervous system myelin. The gene which encodes PMP22 maps to human chromosome 17p11.2.

     

    应用推荐稀释比例
    {ICC/IF}{1:50-200}
    {IF}{1:100-500}

     

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