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- bs-6044R-HRP
- 2025年10月15日
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100ul
| 产品编号 | bs-6044R-HRP |
| 英文名称 | DLL4 Rabbit pAb, HRP conjugated |
| 中文名称 | HRP标记的δ样蛋白4抗体 |
| 英文别名 | deltaD; delta4; delta-like 4(Drosophila); delta-like 4 homolog(Drosophila); Drosophila delta homolog 4; delta-like 4 homolog; delta-like 4 protein; Aei; After eight; dld; DLL4_HUMAN; delta-like protein 4; Drosophila delta homolog 4; delta 4 precursor; delta 4; delta ligand 4; notch ligand delta-2; hdelta2; MGC126344; notch ligand DLL4. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human DLL4 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Cell Cycle > Cell differentiation Epigenetics and Nuclear Signaling > Cell cycle > Cell Differentiation Neuroscience > Neurology process > Notch Pathway |
| 亚基 | Binds to Notch-1 and Notch-4 (By similarity). |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein (Probable). |
| 组织特异性 | Expressed in vascular endothelium. |
| 翻译后修饰 | Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation. |
| 相似性 | Contains 1 DSL domain. Contains 8 EGF-like domains. |
| 功能 | Plays a role in the Notch signaling pathway. Activates Notch-1 and Notch-4. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. Notch proteins have been found to be overexpressed or rearranged in human tumors. Ligands for Notch include Jagged, Jagged-2 and Delta. While blocking the differentiation of progenitor cells into the B-cell lineage, Delta promotes the emergence of a population of cells with T cell/NK-cell characteristics. The protein is a membrane protein expressed in heart, pancreas, brain and muscle during gastrulation and early organogenesis and in adult heart and lung. Delta-4 is a membrane protein that activates Notch-1 and Notch-4. It is expressed in a wide range of adult and fetal tissues, especially in vascular endothelium. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验affinity chromatography and conjugated with horseradish peroxidase (HRP). Formulation Supplied as a 0.2 μm filtered solution in phosphate-buffered saline (PBS) (pH 7.0) with stabilizers. Storage Neat samples can be stored at 2° - 8° C
Western Immunoblotting of Proteins
. For a mouse monoclonal antibody, a goat-anti-mouse HRP conjugated antibody is recommended, for a rabbit polyclonal antibody, a goat-anti-rabbit HRP conjugated antibody is advisable. 7. Wash the nitrocellulose membrane five times for 3 to 5 minutes
Western Immunoblotting of Proteins
antibody, a goat-anti-mouse HRP conjugated antibody is recommended, for a rabbit polyclonal antibody, a goat-anti-rabbit HRP conjugated antibody is advisable. 7. Wash the nitrocellulose membrane five times for 3 to 5 minutes each with either water
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