OPRD1 | DOR-1 Ab Blocking Peptide(bs-10396P)-500ug产品图

OPRD1 | DOR-1 Ab Blocking Pept

ide(bs-10396P)-500ug
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  • bs-10396P
  • 2026年10月10日
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      500ug

    产品编号bs-10396P
    英文名称OPRD1 Antibody Blocking Peptide
    中文名称D型*片受体封闭多肽
    英文别名Delta type opioid receptor; Delta type opioid receptor DOR 1; DOR 1; DOR1; mDOR; Nbor; Opioid receptor delta 1; OPRD; OPRD1; OPRD_HUMAN; Delta-type opioid receptor; D-OR-1; DOR-1.
    纯化方法HPLC
    研究领域

    Neuroscience > Neurotransmission > Receptors / Channels > GPCR > Opioid Receptors

    亚基Interacts with GPRASP1.
    亚细胞定位Cell membrane; Multi-pass membrane protein.
    组织特异性Abundant in lymphoid tissues.
    翻译后修饰Glycosylation is tissue specific. Sialylation of N-glycans at Asn-93 in brain and at Asn-42, Asn-93 and Asn-117 in thymus.
    相似性Belongs to the G-protein coupled receptor 1 family.
    功能Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. receptor for enkephalins.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The opioid receptors are G-protein coupled, seven-transmembrane domain receptors for enkephalins, endorphins, and dynorphins. Three different opioid receptor subtypes (kappa , delta, and mu) were first identified by their different selectivities for various naturally occurring alkaloid opioid ligands, and subsequently confirmed by molecular cloning. The amino acid sequences of the opioid receptor subtypes are ~70% homologous, and are similar to somatostatin receptors (SSTRs) showing ~40 % homology with SSTR1. G-protein binding is thought to occur at the third intracellular loop of the opioid receptors, which is also the location of consensus sequences for phosphorylation of the receptor. Interestingly, the genes encoding the specific receptor subtypes are found on different chromosomes in both the human and mouse genomes.

     

     

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