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| 产品编号 | bs-14640P |
| 英文名称 | ETAA Antibody Blocking Peptide |
| 中文名称 | 尤文氏瘤相关抗原1封闭多肽 |
| 英文别名 | Etaa1; ETAA1_HUMAN; Ewing''s tumor-associated antigen 1; Ewing''s tumor-associated antigen 16; ETAA16. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Tumor immunology > Tumor-associated antigens |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines. |
| 翻译后修饰 | Phosphorylated upon DNA damage, probably by ATM or ATR. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ETAA16 (Ewing's tumor-associated antigen 16), also known as ETAA1, is a 926 amino acid cytoplasmic protein that is highly expressed in kidney, brain, liver and Ewing tumor cell lines. ETAA16 undergoes post-translational phosphorylation following DNA damage, most likely by either ATM or ATR, and is suggested to function as a tumour-specific cell surface antigen in Ewing's family of tumour cell lines. The gene encoding ETAA16 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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