GPC2 | Glypican-2 Ab Blocking Peptide(bs-13450P)-500ug产品图

GPC2 | Glypican-2 Ab Blocking

Peptide(bs-13450P)-500ug
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  • ¥880
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  • bs-13450P
  • 2026年10月10日
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    • 技术资料
    • 规格:

      500ug

    产品编号bs-13450P
    英文名称GPC2 Antibody Blocking Peptide
    中文名称磷脂酰基醇蛋白聚糖2封闭多肽
    英文别名Glypican-2; Gpc2; GPC2_HUMAN; Secreted glypican-2.
    纯化方法HPLC
    亚细胞定位Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side._x000D_
    Secreted glypican-2: Secreted, extracellular space.
    相似性Belongs to the glypican family.
    功能Cell surface proteoglycan that bears heparan sulfate. May fulfill a function related to the motile behaviors of developing neurons.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Glypican-1 (GPC1), glypican-2 (GPC2) and glypican-3 (GPC3) are members of the glypican family of heparan sulfate proteoglycans, which attach to the cell membrane via a glycosylphosphatidylinositol (GPI) anchor. Cell-surface heparan sulfate proteoglycans participate in molecular events that regulate cell adhesion, migration, and proliferation. Glypican-2, a cell surface proteoglycan bearing heparan sulfate, may have a function related to the motile behaviors of developing neurons. Ligation of cell-surface glypican-2 with midkine (MK) or an; against epitope-tagged glypican-2 induces cell adhesion and promotes neurite outgrowth. MK binds to heparan sulfate chains of glypican-2 in a manner similar to syndecan-3, but different localization of epitope-tagged glypican-2 and syndecan-3 on the surface of N2?cells suggests that they may play different roles in MK-mediated neural function.

     

     

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