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- 技术资料
- 规格:
500ug
| 产品编号 | bs-13450P |
| 英文名称 | GPC2 Antibody Blocking Peptide |
| 中文名称 | 磷脂酰基醇蛋白聚糖2封闭多肽 |
| 英文别名 | Glypican-2; Gpc2; GPC2_HUMAN; Secreted glypican-2. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side._x000D_
Secreted glypican-2: Secreted, extracellular space. |
| 相似性 | Belongs to the glypican family. |
| 功能 | Cell surface proteoglycan that bears heparan sulfate. May fulfill a function related to the motile behaviors of developing neurons. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Glypican-1 (GPC1), glypican-2 (GPC2) and glypican-3 (GPC3) are members of the glypican family of heparan sulfate proteoglycans, which attach to the cell membrane via a glycosylphosphatidylinositol (GPI) anchor. Cell-surface heparan sulfate proteoglycans participate in molecular events that regulate cell adhesion, migration, and proliferation. Glypican-2, a cell surface proteoglycan bearing heparan sulfate, may have a function related to the motile behaviors of developing neurons. Ligation of cell-surface glypican-2 with midkine (MK) or an; against epitope-tagged glypican-2 induces cell adhesion and promotes neurite outgrowth. MK binds to heparan sulfate chains of glypican-2 in a manner similar to syndecan-3, but different localization of epitope-tagged glypican-2 and syndecan-3 on the surface of N2?cells suggests that they may play different roles in MK-mediated neural function. |
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GPC2 | Glypican-2 Ab Blocking Peptide(bs-13450P)-500ug
¥880






