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- Bioss
- bs-13396P
- 2026年10月10日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-13396P |
| 英文名称 | GPX2 Antibody Blocking Peptide |
| 中文名称 | 谷胱甘肽过氧化酶2封闭多肽 |
| 英文别名 | Gastrointestinal glutathione peroxidase; GI GPx; Glutathione peroxidase 2 (gastrointestinal); Glutathione peroxidase 2; Glutathione peroxidase gastrointestinal; Glutathione peroxidase related protein 2; Glutathione peroxidase-gastrointestinal; Glutathione peroxidase-related protein 2; GPRP; GPRP-2; GPx 2; GPx-2; GPx-GI; GPX2; GPX2_HUMAN; GSHPx 2; GSHPx GI; GSHPx-2; GSHPx-GI. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Other Antibodies > Oxidative Stress Metabolism > Pathways and Processes > Redox metabolism > Antioxidants Metabolism > Pathways and Processes > Redox metabolism > Oxidative stress |
| 亚基 | Homotetramer. |
| 亚细胞定位 | Cytoplasm. Mainly cytoplasmic. |
| 组织特异性 | Mostly in liver and gastrointestinal tract, not found in heart or kidney. |
| 相似性 | Belongs to the glutathione peroxidase family. |
| 功能 | Could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides. Tert-butyl hydroperoxide, cumene hydroperoxide and linoleic acid hydroperoxide but not phosphatidycholine hydroperoxide, can act as acceptors. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes. GPx enzymes reduce lipid hydroperoxides to alcohols, and reduce free hydrogen peroxide to water. GPx members are among the few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. There are eight GPx homologs (GPx-1–8). GPx-1 plays an important role in the antioxidant defense of the vascular wall and neural cells in response to oxidative stress. GPx-2 is the major isoform in the lungs and its basal or inducible expression is dependent on Nrf2. GPx-3 is under regulation by hypoxic stress and the expression and deficiency of GPx-3 is associated with cardiovascular disease and stroke. GPx-5 is selenium-independent; it is bound to the acrosome of sperm, where it may protect sperm from premature acrosome reaction in the epididymis. |
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GPX2 | GPx-GI Ab Blocking Peptide(bs-13396P)-500ug
￥880
