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EIF1AD Antibody Blocking Pepti

de(bs-14531P)-500ug
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  • ¥880
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  • bs-14531P
  • 2025年10月16日
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      500ug

    产品编号bs-14531P
    英文名称EIF1AD Antibody Blocking Peptide
    中文名称EIF1AD蛋白封闭多肽
    英文别名EIF1A_HUMAN; EIF1AD; Eukaryotic translation initiation factor 1A domain containing; Eukaryotic translation initiation factor 1A domain containing protein; Eukaryotic translation initiation factor 1A domain-containing protein; Haponin; Probable RNA binding protein EIF1AD; Probable RNA-binding protein EIF1AD.
    纯化方法HPLC
    亚基Interacts with GAPDH and STAT1.
    亚细胞定位Nucleus.
    组织特异性Expressed in the glioblastoma cell line U-87MG, the embryonic kidney cell line HEK-293, the pancreatic carcinoma cell line PANC-1, the breast carcinoma cell line MCF-7, the lung cancer cell line NCI-H460, and the chronic myelogenous leukemia cell line K-562.
    相似性Belongs to the EIF1AD family.
    Contains 1 S1-like domain.
    功能Plays a role into cellular response to oxidative stress. Decreases cell proliferation.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料eIF1AD is a 165 amino acid protein that belongs to the eIF1AD family and contains one S1-like domain. eIF1AD localizes to nucleus and is expressed in the glioblastoma cell line U-87 MG, the embryonic kidney cell line HEK-293, the pancreatic carcinoma cell line PANC-1, the breast carcinoma cell line MCF7, the lung cancer cell line NCI-H460, and the chronic myelogenous leukemia cell line K-562. eIF1AD interacts with GAPDH and may function to reduce cell proliferation. The gene encoding eIF1AD maps to human chromosome 11q13.1. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in chromosome 11.

     

     

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