- ￥880
- Bioss
- bs-16221P
- 2026年10月10日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-16221P |
| 英文名称 | GALNT5 Antibody Blocking Peptide |
| 中文名称 | GalNAc-T5蛋白封闭多肽 |
| 英文别名 | GALNAC T5; N acetylgalactosaminyltransferase; Polypeptide GalNAc transferase 5; polypeptide N -acetylgalactosaminyltransferase 5; pp GaNTase 5; Protein UDP acetylgalactosaminyltransferase 5; UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 5; UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 5. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with EXT2. Does not interact with EXT1, EXTL1 or EXTL3. |
| 亚细胞定位 | Cell Membrane and Golgi Apparatus |
| 相似性 | Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. Contains 1 ricin B-type lectin domain._x000D_ |
| 功能 | GALNT5 can catalyze the initial reaction in O-linked oligosaccharide biosynthesis,the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. GALNT5 has activity toward EA2 peptide substrate, but it has a weak activity toward Muc2 or Muc1b substrates. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T5 (Polypeptide N-acetylgalactosaminyltransferase 5), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5, is a 940 amino acid protein that displays enzymatic activity toward EA2 peptide substrate with weaker activity toward Muc2 or Muc 1b substrates. Its N-terminal domain is involved in substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. EXT2 directly interacts with GalNAc-T5, suggesting that these proteins may corroborate in glycosaminoglycan synthesis. |
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GALNT5 | GalNAc-T5 Ab Blocking Peptide(bs-16221P)-500ug
￥880
