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Recombinant human BMP-7 protei

n (Active, HEK293)(bs-48017P)-10ug/50ug/500ug
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  • ¥2080 - 28000
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  • bs-48017P
  • 2025年10月16日
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      10ug/50ug/500ug

    规格:10ug产品价格:¥2080.0
    规格:50ug产品价格:¥6800.0
    规格:500ug产品价格:¥28000.0
    产品编号bs-48017P
    英文名称Recombinant human BMP-7 protein (Active, HEK293)
    中文名称重组人骨形态发生蛋白-7 (活性的, Tag free)
    英文别名rhBMP-7; Bone morphogenetic protein 7 precursor; osteogenic protein 1; BMP7; OP-1; BMP 7; Bone morphogenic protein 7; Eptotermin alfa; OP 1; OP1; BMP7_HUMAN. ;Recombinant human BMP-7 protein (Active, HEK293)
    中文别名人骨形态发生蛋白-7重组蛋白; 重组人骨形态发生蛋白-7; 人重组骨形态发生蛋白-7; 重组人BMP7;
    性状Lyophilized
    纯化方法AC
    实际分子量30-38 kDa
    浓度>0.5 mg/ml
    储存液Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization.
    研究领域

    Cancer > Cell cycle > Cell differentiation

    Cell Biology > Cell Cycle > Cell differentiation

    Developmental Biology > Organogenesis > Excretory system development > Kidney development

    Developmental Biology > Organogenesis > Nervous system development

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipid metabolism

    Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > Structures > Bone

    Signal Transduction > Growth Factors/Hormones > TGF

    Stem Cells > Signaling Pathways > TGF beta > Secreted

    亚基Homodimer; disulfide-linked. Interacts with SOSTDC1. Interacts with TWSG1.
    亚细胞定位Secreted.
    组织特异性Expressed in the kidney and bladder. Lower levels seen in the brain.
    翻译后修饰Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms (PubMed:17977014).
    相似性Belongs to the TGF-beta family.
    功能Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
    保存条件Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq].

     

     

    产品细节图片1
    The purity of the protein is greater than 95% as determined by reduced and non reduced SDS-PAGE

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