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- 2025年10月16日
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| 规格： | 10ug | 产品价格： | ￥2080.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥6800.0 |
| 规格： | 500ug | 产品价格： | ￥28000.0 |
| 产品编号 | bs-48015P |
| 英文名称 | Recombinant human BMP-2 protein (Active, HEK293) |
| 中文名称 | 重组人骨形态发生蛋白-2 (活性的, Tag free) |
| 英文别名 | rhBMP-2; Bone morphogenetic protein 2; BMP 2; BMP 2A; BMP2A; BMP-2; BMP2_HUMAN; Recombinant human BMP-2 protein (Active, HEK293) |
| 中文别名 | 人骨形态发生蛋白-2重组蛋白; 重组人骨形态发生蛋白-2; 人重组骨形态发生蛋白-2; 重组人BMP2; |
| 性状 | Lyophilized |
| 纯化方法 | AC |
| 实际分子量 | 30-38 kDa |
| 浓度 | ＞0.5 mg/ml |
| 储存液 | Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
| 研究领域 | Cancer > Growth factors > TGF Cardiovascular > Angiogenesis > Growth Factors > TGF Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > Structures > Bone Signal Transduction > Growth Factors/Hormones > TGF Stem Cells > Neural Stem Cells > Extracellular Stem Cells > Signaling Pathways > TGF beta > Secreted |
| 亚基 | Homodimer; disulfide-linked. Interacts with SOSTDC1. Interacts with GREM2, RGMA, RGMB and RGMC. Interacts with ASPN. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine. |
| 相似性 | Belongs to the TGF-beta family. |
| 功能 | Induces cartilage and bone formation. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis. |
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