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SBEM Antibody Blocking Peptide

(bs-17247P)-500ug
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  • ¥880
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  • bs-17247P
  • 2025年10月16日
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      500ug

    产品编号bs-17247P
    英文名称SBEM Antibody Blocking Peptide
    中文名称粘蛋白样蛋白1封闭多肽
    英文别名mucin like 1; mucin-like 1; Mucin-like protein 1; MUCL1; MUCL1_HUMAN; Protein BS106; Small breast epithelial mucin.
    纯化方法HPLC
    亚细胞定位O-glycosylated.
    组织特异性Expressed in mammary, salivary glands and prostate. Also detected in lung. Mainly expressed in cancer cell lines of breast origin. Highly expressed in lymph node-positive compared with node-negative tumors. Detected in all lymph node containing metastatic cells.
    翻译后修饰O-glycosylated.
    功能May play a role as marker for the diagnosis of metastatic breast cancer.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料SBEM is a 90 amino acid secreted membrane protein that may play a role as marker for the diagnosis of metastatic breast cancer. SBEM contains three tandem copies of a neutral octapeptide core repeat, and its N- and C-terminal regions are charged and fairly polar. These features are similar to many sialomucins, although the SBEM protein lacks a transmembrane domain and is shorter than most other known epithelial mucins. Expressed in mammary, salivary glands, prostate and also in lung, SBEM is mainly expressed in cancer cell lines of breast origin. SBEM is also highly expressed in lymph node-positive compared with node-negative tumors and in all lymph node containing metastatic cells. The SBEM gene is conserved in chimpanzee, cow, mouse, rat, chicken, zebrafish, C.elegans and M.grisea, and maps to human chromosome 12q13.2.

     

     

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