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- bs-14514P
- 2025年10月16日
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| 产品编号 | bs-14514P |
| 英文名称 | EFCAB6 Antibody Blocking Peptide |
| 中文名称 | EFCAB6蛋白封闭多肽 |
| 英文别名 | DJBP; CAP binding protein complex interacting protein 1; DJ1 binding protein; DJBP; EFCB6_HUMAN; EF hand calcium binding domain 6; FLJ23588. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > Nuclear Receptors > Testosterone Epigenetics and Nuclear Signaling > Transcription > Other factors Signal Transduction > Signaling Pathway > Nuclear Signaling > Nuclear Hormone Receptors > Testosterone |
| 亚基 | Binds PARK7. Part of a ternary complex containing PARK7, EFCAB6/DJBP and AR. |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Specifically expressed in the testis. |
| 相似性 | Contains 17 EF-hand domains. |
| 功能 | Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ1 antagonizes this inhibition by abrogation of this complex. Six named isoforms produced by alternative splicing. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a protein which directly binds the oncogene DJ-1 and androgen receptor to form a ternary complex in cells. This binding protein recruits histone-deacetylase complexes in order to repress transcription activity of androgen receptor. This protein may also play a role in spermatogenesis and fertilization. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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