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GSDMB Antibody Blocking Peptid

e(bs-13291P)-500ug
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  • ¥880
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  • bs-13291P
  • 2025年10月16日
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      500ug

    产品编号bs-13291P
    英文名称GSDMB Antibody Blocking Peptide
    中文名称GSDML蛋白封闭多肽
    英文别名Gasdermin like; 123; 156; Gasdermin B; Gasdermin like protein; Gasdermin-B; Gasdermin-like protein; GSDMB; GSDMB_HUMAN; GSDML; PP4052; PRO2521.
    纯化方法HPLC
    研究领域

    Cell Biology > Other Antibodies > Other Antibodies

    亚细胞定位Cytoplasm. Vesicular localization in the apical region of gastric chief cells and colonic surface mucous cells, and the basal region of neuroendocrine cells.
    组织特异性Expressed in gastric, liver and colon cell lines, carcinomas and non-lesional tissues.
    相似性Belongs to the gasdermin family.
    功能May play a role as secretory or metabolic product involved in secretory pathway. May also play a role in achieving and maintaining the final differentiation state of epithelial cells.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料GSDML is a member of the GSDMDC (gasdermin-domain containing) family of proteins. Members of the GSDMDC family are involved in a wide variety of cellular processes, including cell-cycle control, extracellular matrix production, differentiation and apoptosis, and have been associated with the development and progression of cancer. GSDML is a widely expressed protein found in both cancerous and non-cancerous tissues localizing to the cytoplasm and in secretory vesicles. The gene encoding GSDML is thought to have been generated by a duplication event of the GSDM1 gene which encodes gasdermin. In addition, various isoforms exist for GSDML.

     

     

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