- ￥880
- Bioss
- bs-12023P
- 2025年10月16日
企业认证
相关产品推荐更多 >
centromeric histone H3-like protein-2 Antibody Blocking Peptide(bs-0483P)-500ug
￥880PEPD Antibody Blocking Peptide(bs-12616P)-500ug
￥880
OPN Antibody Blocking Peptide(bs-0026P)-500ug
￥880Recombinant EV71 polyprotein 3CD protein, His(bs-49068P)-100ug/500ug/20ug
￥580PEX6 Antibody Blocking Peptide(bs-12625P)-500ug
￥880
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 规格：
500ug
| 产品编号 | bs-12023P |
| 英文名称 | GPCR GPR102 Antibody Blocking Peptide |
| 中文名称 | G蛋白偶联受体102封闭多肽 |
| 英文别名 | G protein coupled receptor 102; G-protein coupled receptor 102; GPR102; TA5; TAAR8; TAAR8_HUMAN; TaR-5; TaR-8; TAR5; Trace amine assiciated receptor 8; Trace amine receptor 5; Trace amine receptor 8; Trace amine-associated receptor 8; TRAR5; GPCR GPR102. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed in kidney and amygdala. Not expressed in other tissues or brain regions tested. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Trace amines are endogenous molecules structurally related to classical biogenic amines that are linked to psychiatric conditions. A family of G-protein coupled receptors referred to as trace-amine-associated receptors (TAAR) are activated by trace amines and are present in very low levels in mammalian tissue. TaRs contain several structural features that are similar to the rhodopsin ∫-adrenergic receptor superfamily, including the positions of the seven transmembrane regions that provide common ligand-binding pockets as well as the short N- and C-terminal domains. TAAR proteins are potential targets for drugs of abuse, such as amphetamine and MDMA, as well as neuropsychiatric disorders including schizophrenia, depression, and attention deficit disorder. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Nature！中美学者共同破译粘附类 GPCR 自激活机制之谜
作用，对 Stachel 序列介导的粘附类受体机制有了深入了解。同时为 Stachel 序列外源短肽设计提供了依据，为靶向粘附类受体相关疾病的鉴定和治疗奠定了基础。 图 3：GPR133-CTF–Gs 和 GPR114-CTF–Gs 复合物结构，来源 Nature 在 Tethered peptide activation mechanism of the adhesion GPCR ADGRG2 and ADGRG4 工作中，研究团队通过冷
同日 4 篇 Nature！中美学者共同破译粘附类 GPCR 自激活机制之谜
Gs 和 GPR114-CTF–Gs 复合物结构，来源 Nature 在 Tethered peptide activation mechanism of the adhesion GPCR ADGRG2 and ADGRG4 工作中，研究团队通过冷冻电镜技术解析了 Stachel 序列激活的 ADGRG2-β-Gs 和 ADGRG4-β-Gs 的复合物结构，揭示了 Stachel 序列与 aGPCR 的直接作用机制，发现 Stachel 序列 5 个疏水氨基酸呈手指状分布，在 Stachel
or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
技术资料暂无技术资料 索取技术资料
