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| 产品编号 | bs-22360P |
| 英文名称 | CTGF Antibody Blocking Peptide |
| 中文名称 | 结缔组织生长因子封闭多肽 |
| 英文别名 | CCN 2; CCN-2; CCN2; Connective Tissue Growth Factor; CTGF; Hcs 24; Hcs24; Hypertrophic chondrocyte specific protein 24; Hypertrophic chondrocyte-specific gene product 24; Insulin-like Growth Factor-Binding Protein 8; MGC102839; NOV 2; NOV2; Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP8; IGFBP-8; connective tissue growth factor precursor; CTGF_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Angiogenesis > Growth Factors Immunology > Secreted Molecules > CCN Family |
| 亚基 | Monomer. |
| 亚细胞定位 | Secreted, extracellular space, extracellular matrix. Secreted. |
| 组织特异性 | Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested. |
| 相似性 | Belongs to the CCN family. Contains 1 CTCK (C-terminal cystine knot-like) domain. Contains 1 IGFBP N-terminal domain. Contains 1 TSP type-1 domain. Contains 1 VWFC domain. |
| 功能 | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009]. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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