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- bs-13259P
- 2025年10月16日
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500ug
| 产品编号 | bs-13259P |
| 英文名称 | SLC6A13 Antibody Blocking Peptide |
| 中文名称 | γ氨基丁酸运载蛋白2封闭多肽 |
| 英文别名 | GABA transport protein; GAT 2; GAT-2; GAT2; Solute carrier family 6 (Neurotransmitter transporter, GABA), member 13; S6A13_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurotransmitter > Amino Acids > GABA Neuroscience > Neurotransmitter > Transporters > GABA |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed in brain, kidney, lung, liver and testis. |
| 相似性 | Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A13 subfamily. |
| 功能 | Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | GABA is a major inhibitory neurotransmitter and the GABAergic transmission is terminated by the rapid Na+/Cl-dependent uptake of through GABA transporters. There are multiple subtypes of GABA transporters (GAT1, GAT2, GAT3; and betaine GABA transporter (BGT-1). There is ~50% homology between each subtypes. GAT1 and GAT3 have been detected in various parts of the brain while GAT2 is found in many tissues. It appears that GAT1 and GAT3 are involved in distinct GABAergic transmission while GAT2 may be important in non-neural functions. GAT2 is a gamma-amino butyric acid (GABA) transporter. It is a 602 amino acid (85kDa) transmembrane protein. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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