- ￥880
- Bioss
- bs-13256P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-13256P |
| 英文名称 | GAB4 Antibody Blocking Peptide |
| 中文名称 | 生长因子受体结合蛋白2相关蛋白4封闭多肽 |
| 英文别名 | GAB2-like; GAB4; GAB4_HUMAN; GRB2 associated binder 2 like protein; GRB2 associated binding protein family member 4; GRB2-associated binder 2-like; GRB2-associated binder 4; GRB2-associated-binding protein 2-like; GRB2-associated-binding protein 4; Growth factor receptor bound protein 2-associated protein 4. |
| 纯化方法 | HPLC |
| 相似性 | Belongs to the GAB family. Contains 1 PH domain. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The Gab family of adaptor proteins function as molecular scaffolds that mediate protein recruit-ment to RTKs. Cytokine/growth factor triggering of protein tyrosine kinase receptors (RTKs) initiates signaling cascades that progress to the nucleus where signals for activation, proliferation and differentiation occur. This scaffolding mechanism represents a critical link in cytokine/growth factor signaling routes. Gab 1-4 contain Pleckstrin homology and potential binding sites for SH2 and SH3 domain-containing proteins. The recruitment of signaling partners to Gab family members is phosphorylation-dependent. Insulin receptor and EGF receptor signaling are among the cascades that rely on Gab family members to elicit a nuclear response to an extracellular stimulus. Gab 4 (GRB2-associated-binding protein 4), also designated GRB2-associated-binding protein 2-like (Gab 2-like), is a 574 amino acid protein that shares 62% sequence similarity with Gab 2 and contains one Pleckstrin homology domain. |
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GAB4 Antibody Blocking Peptide(bs-13256P)-500ug
￥880
