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JTB Antibody Blocking Peptide(

bs-17212P)-500ug
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  • ¥880
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  • bs-17212P
  • 2025年10月16日
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      500ug

    产品编号bs-17212P
    英文名称JTB Antibody Blocking Peptide
    中文名称前列腺雄激素调节蛋白封闭多肽
    英文别名hJT; HJTB; HSPC222; JTB; JTB_HUMAN; Jumping translocation breakpoint; Jumping translocation breakpoint protein; OTTHUMP00000034759; PAR; PAR protein; Prostate androgen regulated protein; Prostate androgen-regulated protein; Protein JTB.
    纯化方法HPLC
    研究领域

    Cell Biology > Other Antibodies > Other Antibodies

    亚细胞定位Membrane. Mitochondrion. Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle. Detected at the centrosome and along spindle fibers during prophase and metaphase. Detected at the midbody during telophase.
    组织特异性Ubiquitous. Expressed in all normal human tissues studied but overexpressed or underexpressed in many of their malignant counterparts.
    相似性Belongs to the JTB family.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.

     

     

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