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- 2025年10月16日
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| 规格： | 100ug | 产品价格： | ￥2280.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥6880.0 |
| 规格： | 20ug | 产品价格： | ￥680.0 |
| 产品编号 | bs-43117P |
| 英文名称 | Recombinant human CD63 protein, hFc (HEK293) |
| 中文名称 | 重组人黑色素瘤相关抗原蛋白 |
| 英文别名 | Lysosomal associated membrane protein 3; CD63 antigen; CD63 antigen melanoma 1 antigen; CD63 molecule; granulophysin; LAMP 3; LAMP3; lysosome associated membrane glycoprotein 3; CD 63; CD63 antigen (melanoma 1 antigen); CD63_HUMAN; gp55; granulophysin; LAMP-3; LIMP; Lysosomal-associated membrane protein 3; Melanoma-associated antigen ME491; NGA; Ocular melanoma-associated antigen; PTLGP40; Tetraspanin-30; Tspan-30; Mast cell antigen AD1; ME491; melanoma 1 antigen; Melanoma associated antigen ME491; Melanoma associated antigen MLA1; MGC72893; MLA 1; MLA1; ocular melanoma associated antigen; OMA81H; Tetraspanin 30; Tspan 30; TSPAN30; Tumor biomarkers; Platelets markers; Recombinant human CD63 protein, hFc (HEK293) |
| 性状 | Lyophilized or Liqui |
| 纯化方法 | AC |
| 理论分子量 | 38.1 |
| 浓度 | ＞0.5 mg/ml |
| 储存液 | PBS (pH7.4). |
| 研究领域 | Cancer > Invasion/microenvironment > ECM > Cell adhesion Cancer > Tumor biomarkers > Tumor antigens Cardiovascular > Blood > Platelets Immunology > Cell Type Markers > CD > Platelets Tags & Cell Markers > Cell Type Markers > Tumor Associated |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Note=Also found in Weibel-Palade bodies of endothelial cells. Located in platelet dense granules. |
| 组织特异性 | Dysplastic nevi, radial growth phase primary melanomas, hematopoietic cells, tissue macrophages. |
| 相似性 | Belongs to the tetraspanin (TM4SF) family. |
| 功能 | This antigen is associated with early stages of melanoma tumor progression. May play a role in growth regulation. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012] |
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文献和实验and secondary structure analysis. PLoS ONE 5: e15027(DOI:10.1371/journal.pone.0015027).6. Bonar, P. and Casey, J.R. 2010. Purification of functional human Cl-/HCO3- exchanger, AE1, over-expressed in Saccharomyces cerevisiae. Protein Express Purif 74: 106-115
Strep/FLAG Tandem Affinity Purification (SF‐TAP) to Study Protein Interactions
Table of Contents Introduction Basic Protocol 1: Strep/Flag Tandem Affinity Purification (SF‐TAP) of Protein Complexes From HEK293 Cells
Simultaneous Real-Time Imaging of Signal Oscillations Using Multiple Fluorescence-Based Reporters
in intracellular Ca2+ levels and PKC translocation to the plasma membrane in response to mGluR1 stimulation in transiently transfected human embryonic kidney (HEK293) cells. The changes in intracellular Ca2+ were imaged using the fluorescent indicator Oregon Green
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