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| 规格： | 100ug | 产品价格： | ￥2280.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥6880.0 |
| 规格： | 20ug | 产品价格： | ￥680.0 |
| 产品编号 | bs-43118P |
| 英文名称 | Recombinant human CD81 protein, hFc (HEK293) |
| 中文名称 | 重组人CD81蛋白 |
| 英文别名 | 26 kDa cell surface protein TAPA 1; 26 kDa cell surface protein TAPA-1; 26 kDa cell surface protein TAPA1; CD 81; CD81 antigen; CD81 molecule; CD81_HUMAN; CVID6; S5.7; TAPA 1; Target of the antiproliferative antibody 1; Tetraspanin 28; Tetraspanin-28; Tetraspanin28; Tspan 28; Tspan-28; Tspan28; Recombinant human CD81 protein, hFc (HEK293) |
| 性状 | Lyophilized or Liqui |
| 纯化方法 | AC |
| 理论分子量 | 36.4 |
| 浓度 | ＞0.5 mg/ml |
| 储存液 | PBS (pH7.4). |
| 研究领域 | Immunology > Adaptive Immunity > B Cells > CD Microbiology > Interspecies Interaction > Host Virus Interaction Microbiology > Protein > Human Protein > Receptor |
| 亚基 | Plays a critical role in HCV attachment and/or cell entry by interacting with HCV E1/E2 glycoproteins heterodimer. Interacts directly with IGSF8. Interacts with CD53 and SCIMP. |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Hematolymphoid, neuroectodermal and mesenchymal tumor cell lines. |
| 翻译后修饰 | Protein exists in three forms with molecular masses between 22 and 27 kDa, and is known to carry covalently linked fatty acids. |
| 相似性 | Belongs to the tetraspanin (TM4SF) family. |
| 功能 | May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May acts a the viral receptor for HCV. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. [provided by RefSeq, Jul 2008] |
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文献和实验-8878.3. Takayama, H. et al. 2008. High-level expression, single-step immunoaffinity purification and characterization of human tetraspanin membrane protein CD81. PLoS ONE 3: e2314 (DOI: 10.1371/journal.pone.0002314).4. Zhong, M. and Molday, R.S. 2010
Strep/FLAG Tandem Affinity Purification (SF‐TAP) to Study Protein Interactions
Table of Contents Introduction Basic Protocol 1: Strep/Flag Tandem Affinity Purification (SF‐TAP) of Protein Complexes From HEK293 Cells
Simultaneous Real-Time Imaging of Signal Oscillations Using Multiple Fluorescence-Based Reporters
in intracellular Ca2+ levels and PKC translocation to the plasma membrane in response to mGluR1 stimulation in transiently transfected human embryonic kidney (HEK293) cells. The changes in intracellular Ca2+ were imaged using the fluorescent indicator Oregon Green
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