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- 2025年10月16日
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500ug
| 产品编号 | bs-14460P |
| 英文名称 | DUSP28 Antibody Blocking Peptide |
| 中文名称 | 双特异性磷酸酶封闭多肽28封闭多肽 |
| 英文别名 | Dual specificity phosphatase 28; DUSP28; DUS28_HUMAN; VHP. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Apoptosis > Intracellular > Associated Proteins Cell Biology > Cell Cycle > Kinases/Phosphatases Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > MAPK Pathway |
| 亚基 | Monomer. |
| 亚细胞定位 | Cytoplasm. Nucleus. |
| 组织特异性 | Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas. |
| 翻译后修饰 | Myristoylation regulates subcellular location, and is necessary for activation of JNK. |
| 相似性 | Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. Contains 1 tyrosine-protein phosphatase domain. |
| 功能 | DUSP28 belongs to the protein-tyrosine phosphatase family, non-receptor class dual specificity subfamily. It contains one tyrosine-protein phosphatase domain. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members. DUSP28 is a 176 amino acid protein that belongs to the protein-tyrosine phosphatase family and non-receptor class dual specificity subfamily. Containing one tyrosine-protein phosphatase domain, DUSP28 is encoded by a gene that maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2, including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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