- ￥880
- Bioss
- bs-1443P
- 2025年10月16日
企业认证
相关产品推荐更多 >
Recombinant Human Thy-1 protein, C-His (HEK293) (bs-43534P)-100ug/500ug/20ug
￥680
SCGB2A2 Antibody Blocking Peptide(bs-2931P)-500ug
￥880CEBPD Antibody Blocking Peptide(bs-13821P)-500ug
￥880
Guinea pig IgM / Cy3(bs-0375P-Cy3)-100ul
￥840Pre-X protein (X protein; ) Antibody Blocking Peptide(bs-2146P)-500ug
￥880
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-1443P |
| 英文名称 | VCP/p97 Antibody Blocking Peptide |
| 中文名称 | 含缬酪肽蛋白封闭多肽 |
| 英文别名 | valosin-containing protein; 15S Mg(2+) ATPase p97 subunit; ATPase p97; IBMPFD; MGC131997; MGC148092; MGC8560; p97; TER ATPase; TERA; transitional endoplasmic reticulum ATPase; valosin-containing protein; yeast Cdc48p homolog; Transitional endoplasmic reticulum ATPase; TER ATPase; 15S Mg(2+)-ATPase p97 subunit; p97. |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers Neuroscience > Neurology process > Neurodegenerative disease > Parkinson's disease > Synuclein Signal Transduction > Protein Trafficking > ER Proteins |
| 亚细胞定位 | Cytoplasm > cytosol. Nucleus. Present in the neuronal hyaline inclusion bodies specifically found in motor neurons from amyotrophic lateral sclerosis patients. Present in the Lewy bodies specifically found in neurons from Parkinson disease patients. |
| 翻译后修饰 | Phosphorylated by tyrosine kinases in response to T-cell antigen receptor activation. Phosphorylated upon DNA damage, probably by ATM or ATR. ISGylated. |
| 相似性 | Belongs to the AAA ATPase family. |
| 功能 | Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (By similarity). Regulates E3 ubiquitin-protein ligase activity of RNF19A. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. [provided by RefSeq, Jul 2008] |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
VCP/p97 Antibody Blocking Peptide(bs-1443P)-500ug
￥880
