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- bs-14429P
- 2025年10月16日
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500ug
| 产品编号 | bs-14429P |
| 英文名称 | DSCAML1 Antibody Blocking Peptide |
| 中文名称 | 唐氏综合症细胞粘附分子2封闭多肽 |
| 英文别名 | Down syndrome cell adhesion molecule 2; Down syndrome cell adhesion molecule like 1; Down syndrome cell adhesion molecule like protein 1; Down syndrome cell adhesion molecule-like protein 1; DSCAM2; DSCAML1; DSCL1_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurology process > Growth and Development > Axonal Guidance Proteins Neuroscience > Neurology process > Neurodegenerative disease Neuroscience > Neurology process > Neurogenesis |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | Detected in heart, liver, pancreas, skeletal muscle, kidney and in brain, in particular in the amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra, thalamus and subthalamus. |
| 相似性 | Contains 6 fibronectin type-III domains. Contains 10 Ig-like C2-type (immunoglobulin-like) domains. |
| 功能 | Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Promotes both isoneuronal self-avoidance for creating an orderly neurite arborization in retinal rod bipolar cells and heteroneuronal self-avoidance to maintain mosaic spacing between AII amacrine cells. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | DSCAML1 is a cell adhesion molecule that contains six Fibronectin type-III domains and ten Ig-like C2-type domains. DSCAML1 is involved in regulating isoneuronal self-avoidance, the tendency for sister arbors to avoid crossing each other and to spread out proportionately over an area. Isoneuronal self-avoidance is important for proper terminal branching (arborization). DSCAML1 also promotes heteroneuronal self-avoidance to maintain mosaic spacing between aII amacrine cells. DSCAML1 is expressed in liver, skeletal muscle, brain, kidney, pancreas and heart and exists as two isoforms produced by alternative splicing events. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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