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- 技术资料
- 规格:
500ug
| 产品编号 | bs-11936P |
| 英文名称 | PLXNA4 Antibody Blocking Peptide |
| 中文名称 | 神经丛蛋白A4封闭多肽 |
| 英文别名 | FAYV2820; KIAA1550; PLEXA4; Plexin-A4; PlexinA4; PLXA4_HUMAN; PLXNA4; PLXNA4A; PLXNA4B; PRO34003; UNQ2820/PRO34003. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurology process > Growth and Development > Axonal Guidance Proteins Neuroscience > Neurology process > Neurogenesis Neuroscience > Neurology process > Neuroregeneration > Neuroregeneration |
| 亚基 | Interacts with NRP1 and NRP2 |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein |
| 翻译后修饰 | Phosphorylated upon DNA damage, probably by ATM or ATR. |
| 相似性 | Belongs to the plexin family. _x000D_ Contains 4 IPT/TIG domains. _x000D_ Contains 3 PSI domains. _x000D_ Contains 1 Sema domain. |
| 功能 | Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Forms a receptor complex with neuropilin-1 and can propagate semaphorin-3A elicited inhibitory signals into cells and neurons. |
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