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- Bioss
- bs-14646P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-14646P |
| 英文名称 | KCNIP4 Antibody Blocking Peptide |
| 中文名称 | A型钾离子通道调节蛋白4封闭多肽 |
| 英文别名 | A type potassium channel modulatory protein 4; a-type potassium channel modulatory protein 4; CALP; calsenilin like protein; Calsenilin-like protein; HGNC:30083; KCHIP 4; KCHIP4; KCIP4_HUMAN; KCNIP 4; Kcnip4; Kv channel interacting protein 4; Kv channel-interacting protein 4; MGC44947; Potassium channel interacting protein 4; Potassium channel-interacting protein 4. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurotransmission > Calcium Signaling > Calcium Binding Proteins Neuroscience > Neurotransmission > Receptors / Channels > Potassium Channels |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | Predominantly expressed in brain. |
| 相似性 | Belongs to the recoverin family. Contains 4 EF-hand domains. |
| 功能 | Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Probably modulates channels density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.3 currents. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
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KCNIP4 Antibody Blocking Peptide(bs-14646P)-500ug
￥880
