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- 2025年10月16日
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500ug
| 产品编号 | bs-1348P |
| 英文名称 | FAF1 Antibody Blocking Peptide |
| 中文名称 | Fas相关1因子封闭多肽 |
| 英文别名 | Fas associated factor 1; CGI; FAF1 protein; Fas (TNFRSF6) associated factor 1; FAS associated factor 1; FLJ37524; hFAF1; HFAF1s; Protein FAF1; CGI 03; FAF1; FAF1_HUMAN; Fas associated protein factor 1; FAS-associated factor 1; UBX domain protein 3A; UBX domain-containing protein 12; UBX domain-containing protein 3A; UBXD12; UBXN3A; TNFRSF6 associated factor 1. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Apoptosis > Intracellular > Associated Proteins |
| 亚基 | Specifically interacts with the cytoplasmic domain of FAS. Interacts with NLRP12 DAPIN/PYRIN domain via its UBA domain. |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Most abundant in testis, slightly less abundant in skeletal muscle and heart, followed by prostate, thymus, ovary, small intestine, and colon. Not detected in the peripheral blood leukocytes. |
| 相似性 | Contains 1 UBA domain. Contains 1 UBX domain. |
| 功能 | Potentiates but cannot initiate FAS-induced apoptosis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | FAF1 (Fas-associated protein factor 1) specifically interacts with the cytoplasmic domain of wild type, but not mutated, Fas in both yeast and mammalian cells. It is transiently expressed in T cells and potentiates Fas-induced apoptosis. FAF1 lacks a DDH (Death domain homologous region), in contrast to TRADD, FADD, and RIP, and cannot induce apoptosis independent of Fas activation. Fas associated factor 1; CGI ; FAF1 protein; Fas (TNFRSF6) associated factor 1; FAS associated factor 1; FLJ37524; hFAF1; HFAF1s; Protein FAF1; TNFRSF6 associated factor 1. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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