- ￥480 - 720
- Bioss
- D62336
- 2025年10月17日
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5mg/10mg
| 规格： | 5mg | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 10mg | 产品价格： | ￥720.0 |
| 产品编号 | D62336 |
| 英文名称 | TAO Kinase inhibitor 1 |
| 理论分子量 | 384.47026 |
| 保存条件 | -20℃ |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | TAO Kinase inhibitor 1 (compound 43) is a selective, ATP-competitive thousand-and-one amino acid kinases (TAOK) inhibitor with IC50s of 11 to 15 nM for TAOK1 and 2, respectively. TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death |
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文献和实验Visualization of Kinase Activity with FRET‐Based Activity Biosensors
Literature Cited Allen, M.D. and Zhang, J. 2006. Subcellular dynamics of protein kinase A activity visualized by FRET
Cortical Neurons Culture to Study c-Jun N-Terminal Kinase Signaling Pathway
Excitotoxicity via N -methyl-d -aspartate receptors (NMDA-r) is a key mechanism of neurodegeneration following ischemia and other brain pathologies. We here describe the use of a fast, reliable and easily
-binding site contributes to poor inhibitor selectivity, issues which have particularly hampered the development of novel kinase inhibitors. We developed a high-throughput screening technology that can discriminate for inhibitors which stabilize
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