- ￥515 - 781
- Bioss
- D57622
- 2025年10月17日
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5mg/10mg
| 规格： | 5mg | 产品价格： | ￥515.0 |
|---|---|---|---|
| 规格： | 10mg | 产品价格： | ￥781.0 |
| 产品编号 | D57622 |
| 英文名称 | Bis(maltolato)oxovanadium(IV) |
| 中文名称 | 双(麦芽醇)氧钒(IV) |
| 英文别名 | BMOV; Bis(maltolato)oxovanadium (IV) |
| 理论分子量 | 317.15 |
| 保存条件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | BMOV is a potent, reversible, competitive and orally active pan-PTP (protein tyrosine phosphatases)inhibitor with insulin-mimicking effects and anti-diabetic properties. BMOV is a potent insulin sensitize. BMOV is shown to improve cardiac dysfunctions in diabetic models. BMOV inhibits HCPTPA, PTP1B, HPTPβ and SHP2 with IC50s of 126 nM, 109 nM, 26 nM and 201 nM, respectivelyr[1][2]. |
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文献和实验1.5‐mm spacers Peristaltic pump and 0.110‐in. i.d., 2.79‐mm PVC tubing 19‐G needles (8‐in. long; 1.00 × 200–mm) with Luer‐connection (e.g., Rometsch GmbH or Popper & Sons) Gradient maker with two chambers
. See Strom, M. S., D. N. Nunn, and S. Lory. 1993. A single bifunctional enzyme, PilD, catalyzes cleavage and N-methylation of proteins belonging to the type IV pilin family. Proc. Natl. Acad. Sci., 90:2404-2408. or Strom, M. S., and S. Lory
Overview of Formation of G‐Quadruplex Structures
. (iii) Two neighboring strands oriented in one direction, and the other two in the opposite direction. (iv) Each strand antiparallel to adjacent neighbors. Blue and red boxes represent guanine bases in the anti and syn conformations, respectively. (D
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