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- D57502
- 2025年10月17日
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1mg/2mg
| 规格： | 1mg | 产品价格： | ￥418.0 |
|---|---|---|---|
| 规格： | 2mg | 产品价格： | ￥594.0 |
| 产品编号 | D57502 |
| 英文名称 | H4 Receptor antagonist 1 |
| 理论分子量 | 316.78 |
| 保存条件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM. |
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文献和实验[3H](+)MK801 Radioligand Binding Assay at the N‐Methyl‐D‐Aspartate Receptor
. Bonhaus, D.W. and McNamara, J.O. 1998. N‐methyl‐D‐aspartate receptor regulation of uncompetitive antagonist binding in rat brain membranes: Kinetic analysis. Mol. Pharmacol. 34:250‐255
Overview of Receptor Allosterism
Figure 1.21.2 Effect of: (A ) negative allosteric modulator, (B ) positive allosteric modulator, or (C ) a competitive antagonist on orthosteric ligand‐receptor occupancy (ρA ). For all the simulations, p K
[D-Arg6 , D-Trp7,9 , Nme Phe8 ]-substance P (6-11) (antagonist G) is a novel class of anti-cancer agent that inhibits small cell lung cancer (SCLC) cell growth in vitro and in vivo and is entering Phase II clinical investigation
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