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Naratriptan hydrochloride(D571

45)-1mg/1mL x 10mM (in DMSO)
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  • ¥256 - 907
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  • D57145
  • 2025年10月17日
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      1mg/1mL x 10mM (in DMSO)

    规格:1mg产品价格:¥256.0
    规格:1mL x 10mM (in DMSO)产品价格:¥907.0
    产品编号D57145
    英文名称Naratriptan hydrochloride
    中文名称盐酸那拉曲坦
    英文别名GR-85548A hydrochloride; Naratriptan HCl; Amerge; Naramig
    理论分子量371.93
    保存条件Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulation of 5-HT1D/1B receptors on sensory nerve endings in the trigeminal system thereby decreasing the release of pro-inflammatory neuropeptides.

     

     

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