- ￥215 - 578
- Bioss
- D56614
- 2025年10月17日
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- 规格：
1mg/1mL x 10mM (in DMSO)
| 规格： | 1mg | 产品价格： | ￥215.0 |
|---|---|---|---|
| 规格： | 1mL x 10mM (in DMSO) | 产品价格： | ￥578.0 |
| 产品编号 | D56614 |
| 英文名称 | SB 271046 hydrochloride |
| 英文别名 | SB 271046A |
| 理论分子量 | 488.45 |
| 保存条件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | SB 271046 hydrochloride is selective, orally active 5-HT6 antagonist (pKi values are 9.02-8.92, 6.35, 6.55, 6.27 at 5-HT6, 5-HT1A, 5-HT1D and D3, and 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and < 4.99 at 5-HT1B, 5-HT1F, α1B, 5-HT2C, 5-HT2A, D2, 5-HT2B, 5-HT7, 5-HT4 and 5-HT1E respectively) and is > 200-fold selective over 55 other receptors, enzymes and ion channels. It increases extracellular aspartate and glutamate in the frontal cortex and exhibits anticonvulsant activity (EC50: 0.16 μM). |
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文献和实验Luyai, A., Lasanajak, Y., Smith, D.F., Cummings, R.D., and Song, X. 2009. Facile preparation of fluorescent neoglycoproteins using p‐nitrophenyl anthranilate as a heterobifunctional linker. Bioconjug. Chem. 20:1618‐1624
Differentiation of Human Embryonic Stem Cells to Cardiomyocytes on Microcarrier Cultures
MAP kinase inhibitor SB203580 (Sigma‐Aldrich, cat. no. S8307) previously dissolved in dimethyl sulfoxide (DMSO; Sigma‐Aldrich, cat. no. D2650)
Assessment of Drug Transporter Function Using Fluorescent Cell Imaging
.R., Chu, X., Dahlin, A., Evers, R., Fischer, V., Hillgren, K.M., Hoffmaster, K.A., Ishikawa, T., Keppler, D., Kim, R.B., Lee, C.A., Niemi, M., Polli, J.W., Sugiyama, Y., Swaan, P.W., Ware, J.A., Wright, S.H., Yee, S.W., Zamek‐Gliszczynski, M.J
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