- ￥239 - 900
- Bioss
- D54375
- 2025年10月17日
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- 详细信息
- 技术资料
- 规格：
1mg/1mL x 10mM (in DMSO)
| 规格： | 1mg | 产品价格： | ￥239.0 |
|---|---|---|---|
| 规格： | 1mL x 10mM (in DMSO) | 产品价格： | ￥900.0 |
| 产品编号 | D54375 |
| 英文名称 | Paritaprevir |
| 中文名称 | 帕利瑞韦 |
| 英文别名 | Veruprevir; ABT-450 |
| 理论分子量 | 765.89 |
| 保存条件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Paritaprevir is an orally bioavailable, synthetic acylsulfonamide inhibitor of the hepatitis C virus (HCV) protease complex comprised of non-structural protein 3 and 4A (NS3/NS4A), with potential activity against HCV genotype 1. Upon administration, paritaprevir reversibly binds to the active center and binding site of the HCV NS3/NS4A protease and prevents NS3/NS4A protease-mediated polyprotein maturation. This disrupts both the processing of viral proteins and the formation of the viral replication complex, which inhibits viral replication in HCV genotype 1-infected host cells. NS3, a serine protease, is essential for the proteolytic cleavage of multiple sites within the HCV polyprotein and plays a key role during HCV ribonucleic acid (RNA) replication. NS4A is an activating factor for NS3. HCV is a small, enveloped, single-stranded RNA virus belonging to the Flaviviridae family, and infection is associated with the development of hepatocellular carcinoma (HCC). |
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Paritaprevir(D54375)-1mg/1mL x 10mM (in DMSO)
￥239 - 900
