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2mg/5mg
| 规格: | 2mg | 产品价格: | ¥467.0 |
|---|---|---|---|
| 规格: | 5mg | 产品价格: | ¥781.0 |
| 产品编号 | D54325 |
| 英文名称 | JAK2 Inhibitor V |
| 英文别名 | Z3; NSC 42834; JAK2 Inhibitor V Z3 |
| 理论分子量 | 344.45 |
| 保存条件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner. |
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文献和实验Methods for the Detection of the JAK2 V617F Mutation in Human Myeloproliferative Disorders
A single acquired mutation in the JAK2 gene has recently been described in human myeloproliferative disorders, including most patients with polycythemia vera and about half of those with essential thrombocythemia and idiopathic myelofibrosis
Recently, a point mutation in the JAK2 gene, JAK2 V617F , was discovered in several myeloid proliferative neoplasms including polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). Demonstration
of each component.2D gel electrophoresis is generally used as a component of proteomics and is the step used for the isolation of proteins for further characterisation by mass spectroscopy. In the lab this technique is used for 2 main purposes, firstly for the large
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